Post-mortem Redistribution of Alprazolam in Rats
نویسندگان
چکیده
منابع مشابه
Post-mortem drug redistribution--a toxicological nightmare.
Detailed human case data is presented to illustrate the dramatic extent of the phenomenon of post-mortem drug redistribution. The data suggests that there is a post-mortem diffusion of drugs along a concentration gradient, from sites of high concentration in solid organs, into the blood with resultant artefactual elevation of drug levels in blood. Highest drug levels were found in central vesse...
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The post-mortem redistribution of a number of psychiatric drugs was investigated. A portion of liver, the gastric contents and blood collected from heart and femoral sites was obtained from 13 cases and analyzed by liquid chromatography-mass spectrometry. Drugs detected included five selective serotonin reuptake inhibitors; venlafaxine, a serotonin/noradrenaline reuptake inhibitor; and risperid...
متن کاملThe time-dependant post-mortem redistribution of antipsychotic drugs.
The post mortem redistribution of ten commonly prescribed antipsychotic drugs (APs) was investigated. Femoral blood was collected from 273 cases at admission to mortuary (AD) and at post-mortem (PM). The PM samples were collected at various times up to nine days after admission and the sample pairs analysed using LC-MS/MS. The drugs included in this study were 9OH-risperidone (paliperidone), am...
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mesentery along the whole of its attachment was found to present an uniform extravasation of blood, commencing from the right iliac fossa and passing upwards along the middle line to the duodenum and to the posterior surface of the stomach. There were also similar patches of extravasation on the surface of the caecum, the horse-shoe curve of the duodenum and a part of the stomach near its splen...
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It is especially appropriate that a paper originating from the Medical Division of the Army Chemical Center be included in this anniversary volume of the Yalc Journal of Biology and Medicine. Dr. Winternitz has been actively connected with chemical warfare medical research from the beginning and particularly during the two wartime periods of greatest activity. During the war against the Central...
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ژورنال
عنوان ژورنال: Prague Medical Report
سال: 2020
ISSN: 1214-6994,2336-2936
DOI: 10.14712/23362936.2020.21